The birthplace of graphene and the stored-program computer, pairing advanced materials leadership with world-class cancer, energy and space science.
Manchester and Lancaster chemists have crystallised uranocenium, the charged form of uranocene first sought in 1968, and shown that covalent electron sharing holds its shape.
By screening electron interactions with a second twisted layer less than a nanometre away, National Graphene Institute researchers watched superconductivity switch off.
A British Journal of Cancer review by Manchester scientists finds hydrogel-based 3D tumour models can mimic drug resistance and cell interactions, reducing reliance on animal testing.
Neutron reflectometry shows the blood-clotting protein builds stacked layers at surfaces rather than tilting upright, overturning a model that stood for two decades.
The first national-scale assessment of canal cooling, simulating over 2,300 canal sections across Britain and Ireland, finds heat-risk hours fall by up to three-quarters.
Genome mining and enzyme engineering by Imperial and Manchester scientists yielded polyene antifungals with better activity and lower toxicity than amphotericin, published in Nature.
Across five studies with 1,233 participants, messages from large language models were rated as emotionally supportive as human ones, and more so for anger and fear.
Crushed concrete from decommissioned sites removed up to 98 per cent of strontium from groundwater in experiments, pointing to cheaper on-site disposal options.
Manchester-led modelling shows disorderly beating cilia move materials over coral more effectively than aligned ones, a framework applicable to human ciliated tissues.
Sediment cores and 3D seismic imaging show methane hydrates beneath the northwest Greenland shelf were rapidly destabilised as the ice sheet withdrew.
Dyeing polyester with fluorescent markers before washing detected up to 280 per cent more microfibres than standard methods, Manchester researchers report.
Manchester biotechnologists evolved an enzyme through eight rounds of engineering to make a key chiral building block of the long-acting HIV capsid inhibitor.
The LHCb collaboration has observed a doubly charmed baryon whose mass matches prediction, resolving a two-decade puzzle, with Manchester-built detectors at the heart of it.
An IBM, Manchester and Oxford collaboration built C13Cl2 atom by atom and used a quantum computer to confirm the first half-Mobius electronic topology in a single molecule.
A Manchester modelling framework links mission requirements to debris exposure, showing collision probability peaks about 50 km above the densest debris band.
Chandra X-ray and James Webb data reveal JADES-ID1, an X-ray-emitting protocluster seen one billion years after the Big Bang, far earlier than thought possible.
Using two beams and one detector, the MicroBooNE collaboration excludes a single sterile neutrino with 95 per cent certainty, with Manchester physicists central to the search.
Collagen fingerprinting of 51 Tasmanian fossils shows the koala and extinct Thylacoleo shared a common ancestor 25 to 35 million years ago, closer than once thought.