Latin America's research powerhouse, spanning tropical medicine, agriculture, physics and genomics from its vast Butantã campus and beyond.
Vivaxin, a candidate developed at USP's School of Pharmaceutical Sciences with partners at UFMG, has won regulatory approval for a Phase 1 trial. No vaccine against Plasmodium vivax is yet available anywhere.
USP economists used digital archaeology and data science to trace the financial flows of the Roman Republic, arguing that economic integration mattered as much as military conquest.
A randomised trial at USP's Hospital das Clínicas found that a behavioural programme to raise daily step counts matched twice-weekly treadmill training in adults with moderate to severe asthma.
USP biologists and engineers used LiDAR to build three-dimensional models of street trees, showing how badly planned pruning creates the asymmetries that make trees vulnerable to wind.
Research at USP's Ribeirão Preto medical school found that higher paternal consumption of ultra-processed food was associated with higher birth weight and localised fat in babies.
A USP Ribeirão Preto laboratory presented a lipid nanoparticle platform that delivers gene-silencing RNA into the skin, targeting psoriasis, vitiligo and chronic wounds.
Physicists at USP's São Carlos institute showed that diagnostic-frequency ultrasound ruptures viral envelopes through acoustic resonance, inactivating SARS-CoV-2 and H1N1 in vitro.
After nearly six years of work, USP researchers produced a gene-edited, cloned piglet, a milestone in the XenoBR programme to supply organs compatible with human patients.
USP medical researchers analysed nearly 600 blood samples and thousands of autoantibodies, finding systemic immune signatures in Alzheimer's, Parkinson's and multiple sclerosis.
Physicists at USP São Carlos built a capacitive sensor that detects the pancreatic cancer biomarker CA19-9 in blood, returning results in about ten minutes.
Experiments at USP's Ribeirão Preto medical school show that stress in adolescence permanently alters excitatory and inhibitory networks in mice, while adult stress effects fade.
USP's nanomedicine group showed that defect-engineered hydroxyapatite particles light up cells for imaging, while a sister system releases chemotherapy only in acidic tumour environments.
USP geoscientists used drone-borne LiDAR to confirm the colossal scale of the Casa de Pedra portal and are now instrumenting the cave to understand its dangerous flood waves.
A probiotic beverage developed at USP's pharmaceutical sciences school raised expression of folate-transport and vitamin D receptor genes in intestinal cells, and protected folate-deficient mice.
A mouthwash built around CANECPI-5, a modified sugarcane protein developed at USP's Bauru dental school, forms a protective film on enamel for patients whose salivary glands were damaged by radiotherapy.
Bakiribu waridza, identified with help from a USP Museum of Zoology specialist, is the first filter-feeding pterosaur found in Brazil and the first animal ever described from a regurgitalite.
USP biomedical scientists published twin studies in Communications Biology showing that STIP1 safeguards stem cell identity while Maspin helps hold epithelial cells in shape.
An eight-week mindfulness programme at USP's Ribeirão Preto nursing school improved pain thresholds and reduced stress in women with chronic temporomandibular disorder.