RE-SHIFT · Dismantling, REdialing, personalizing, and implementing task SHIFTing psychosocial interventions to treat and prevent common mental disorders in low-resource settings

RE-SHIFT focuses on preventing and treating common mental disorders in people living in low-resource settings. It aims at (a) dismantling psychosocial interventions delivered by non specialist providers into their components, (b) evaluating each component efficacy and redialing the most effective components into a novel task shifting psychosocial intervention, and (c) implementing findings through a worldwide coverage e-learning platform. RE-SHIFT will also develop a publicly available calculator to estimate the efficacy of each component based on individual participant characteristics. Starting from an analysis of individual participant data from all randomized controlled trials conducted in the field of global mental health available on the matter, RE-SHIFT will pioneer a sophisticated study design to unravel which components work best and for whom, identifying at the same time how participant, provider and delivery characteristics moderate the outcome and how beneficial effects of the psychosocial task shifting interventions are mediated. With this information it will be possible to tailor interventions according to the specific needs of diverse populations, allowing the ""RE-SHIFTing"" of available resources to the best of their use. A mainstay of RE-SHIFT is to activate ambitious implementation and dissemination measures to let a different range of stakeholders, lay people, organizations, general public, patient and family organization advocates to know about the project, its aims, deliverables, and potential impact of its findings on the society. Training activities will last for the entire duration of the project, and results will be presented in top-tier international conferences and submitted to high impact factor international peer-reviewed journals. RE-SHIFT is concrete and ambitious, its findings will be globally applicable and serve as a blueprint and impetus for other projects aiming at promoting mental health equity.""