LAPASO · Label Free Particle Sorting

LAPASO will provide a unique training opportunity for 15 fellows in a highly interdisciplinary and intersectorial environment with the overarching scientific objective of advancing diagnostics in a wide range of critical medical conditions using advanced microfluidics and nanobiotechnology integration.Microfluidic particle fractionation based on the inherent properties of e.g. cells, microorganisms, organelles offers significant improvements over conventional techniques in terms of ease of handling and usage, speed and reductions in cost. We will consolidate the field at the European level and create a unique comprehensive training program that rests on solid experimental and theoretical foundations.Three leading experimental groups will provide the technological development of microfluidic label-free sorting based on dielectrophoresis, deterministic lateral displacement and acoustophoresis with strong support from leading theorists. The technology will be used to address key medical questions defined by our biomedical collaborators and partners in parasitology, bacteriology and oncology. Three companies are engaged to provide an industrial perspective on our work, specifically from a technological point of view with respect to treatment of infectious disease, advanced fluidics handling and DNA analysis and mass production of devices.To ensure an efficient transfer of knowledge across disciplines and across sectors the work will take place in close collaboration through frequent ESR/ER exchange between the partners.The training of a next generation of researchers will ensure the implementation and dissemination of these powerful novel key techniques to industry and end-users.Through the strong interdisciplinary and intersectorial character of the network, the ESR and ER will receive a uniquely comprehensive training above what a traditional postgraduate training would offer that in turn gives them a strong competitive advantage in both academia and industry.