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Funded Projects › HORIZON

HeartRestore · Next-generation heart bypass grafts to naturally restore cardiovascular function.

HORIZONStatus: SIGNED1 December 202230 November 2025EU funding €2,481,701Call HORIZON-EIC-2021-ACCELERATOROPEN-01

Coronary Artery Disease is caused by narrowing of heart arteries that supply blood, often due to atherosclerosis. Coronary artery bypass grafting (CABG) is the gold standard surgery to treat it, and it commonly involves harvesting patient’s veins from the legs as grafts. This collection affects patients causing chronic pain and costly complications. It also has a high failure rate with >20% implants occluded after 1 year.Xeltis has developed a unique restorative vascular graft (XABG) that eliminates the need for vein harvesting. The implant provides a homing structure for cells in which cardiac and vascular tissues can be naturally restored, with the related advantages and benefits for patients and the healthcare system. We have proven our technology in first niche applications, as well as completed pre-clinical studies successfully for XABG. Now, we plan to perform a full clinical validation to obtain a CE mark in Europe and start market deployment and commercial up-scaling.

Consortium · 2 organisations

coordinator

XELTIS BV

NL · €2,481,701

thirdParty

XELTIS AG

CH

Research fields

View the official record on CORDIS →

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Source: CORDIS, Publications Office of the European Union. Global Research Partnerships surfaces open EU research data to help you find collaborators; we are not affiliated with the European Union.