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DNAMI · Aromatic oligoamide foldamers as mimics of double helical DNA
The aim of this project is to design and synthesize helically folded aromatic oligoamides that chemically and structurally mimic the surface of double stranded DNA. The potency of these foldamers to interact with DNA processing enzymes relevant in cancer therapy will be assessed in order to establish structure-activity relationships. The research program primarily involves the chemical synthesis of novel anion bearing foldamers as well as structural investigations
Consortium · 1 organisation
coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
FR · €201,932
Research fields
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